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Looking for lakefront homes for sale on Caloosahatchee River? Find waterfront real estate here. Located in Lee County, Florida. Discover the best lake front listings - properties, land, and acreage to build your dream lake house, cottage or cabin on. Search for an agent who specializes in lake property to help you buy or sell a home.

Lakehouse.com has 1821 property for sale on Caloosahatchee River, as well as homes, lots, land and acreage in N. Fort Myers, Fort Myers, North Fort Myers. Median home price: $842,846, lot price: $354,055. 

1240 Coconut Drive

6 11.0   Sf: 10493   Yr: 2013  Acres: 2.180

A true crown jewel of Southwest Florida, this Palladian-inspired waterfront estate stands in a class entirely its own. Offering a level of craftsmanship, scale, and resilience more often associated...

3836 Harold Avenue

5 8.0   Sf: 8701   Yr: 2012  Acres: 0.655

*Legacy Awaits* Welcome to an unparalleled masterpiece, an architectural marvel built by Gargiula Construction, that transcends time and trends. This extraordinary property draws inspiration from the...

14201 Bay Drive

5 7.0   Sf: 6822   Yr: 2024  Acres: 0.692

Don't miss this boater's paradise with direct (no bridges) deep water Gulf Access only minutes from the river. This one of a kind property features ultimate privacy in this exclusive, gated...

23631 Palm Beach Boulevard

Acres: 105.130

Unlock the potential of this 105.13+/- acre parcel located in Alva, boasting over 3,000+/- feet of Caloosahatchee River frontage and 4,000+/- feet along Palm Beach Blvd (SR 80). Whether you're...

3715 SE 21st Place

6 8.0   Sf: 5029   Yr: 2024  Acres: 0.501

Spectacular Riverfront Estate: More than 1/2 acre lot (21,824sqf.) Discover unparalleled luxury in this stunning contemporary masterpiece situated on the prestigious Caloosahatchee River. This...

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14994 Bonaire Circle

6 6.0   Sf: 6394   Yr: 2015  Acres: 0.393

LUXURY RIVERFRONT LIVING. Custom Carlton-Naumann 6,394 Sq. ft. masterpiece, where a rare opportunity with unobstructed water views awaits you. Expansive pool and new 320-foot dock, Boat lift and...

15500 Cook Road

Acres: 4.300

This is the perfect parcel of land offering multiple options. Property is zoned RS-1 and offers 300 ft on the Caloosahatchee river with private gated access. Option 1: Build an exclusive Riverfront...

1518 Hermitage Lane

4 5.0   Sf: 5450   Yr: 2001  Acres: 0.333

Welcome to 1518 Hermitage Ln, a breathtaking statement of modern luxury located within the prestigious, gated Hermitage community of Cape Coral with southern exposure and spectacular water views...

846 Cypress Lake Circle

4 5.0   Sf: 4735   Yr: 2025  Acres: 0.310

Experience luxury living in the prestigious Town and River community, renowned for its multimillion-dollar homes and exceptional deep-water boating access. This new construction home, scheduled for...

5831 SW 1st Avenue

5 8.0   Sf: 5557   Yr: 2024  Acres: 0.257

New Construction, riverfront property. 5 bed, 8 bath, family room, game room, office, additional butler kitchen, and a glass cube elevator. This High-end project from Exclusive Designs features a...

2920 Fort Denaud Road

3 5.0   Sf: 4514   Yr: 2006  Acres: 8.000

Welcome to your very own slice of paradise on a high and dry private island! This stunning retreat is accessible via a concrete bridge and features an automated gate for that extra touch of...

1504 SW 57th Street

5 5.0   Sf: 6950   Yr: 2007  Acres: 0.305

River-like, intersecting mega-wide canal views-without the river drawbacks. Just steps from Cape Harbour, this waterfront estate is a reimagined modern masterpiece offering true resort-style luxury...

4831 Conover Court

4 5.0   Sf: 5700   Yr: 2005  Acres: 0.367

Experience unparalleled waterfront luxury in the prestigious deep-water boating community of Palmetto Point. This exquisite move-in ready residence has been completely reimagined, blending coastal...

3402 W Riverside Drive

5 7.0   Sf: 8173   Yr: 1989  Acres: 0.714

Located just off historic McGregor Boulevard, this elevated, all-concrete riverfront estate offers a rare combination of scale, security, and privacy along the Caloosahatchee River. Set on a private...

5653 Riverside Drive

4 5.0   Sf: 4562   Yr: 2026  Acres: 0.268

*** Luxurious new construction contemporary Riverfront Estate on the Caloosahatchee River in the prestigious Yacht Club Area! *** Experience unmatched modern craftsmanship in this brand-new 4,562 sq...

6901 Deep Lagoon Lane

4 5.0   Sf: 3674   Yr: 2026  Acres: 0.476

Brand new riverfront luxury home in Town & River Estates is underway by renowned builder Edge Water Development Group! Situated on magnificent Deep Lagoon this premiere waterfront property overlooks...

771 Cypress Lake Circle

5 7.0   Sf: 6452   Yr: 1997  Acres: 0.410

Discover an extraordinary opportunity to own one of the BEST waterfront homes in Southwest Florida. Located in Town & River, one of areas BEST boating communities, this stunning contemporary coastal...

6005 W Riverside Drive

5 6.0   Sf: 6320   Yr: 2006  Acres: 0.334

Welcome to 6005 W Riverside Drive. This stunning Caloosahatchee river front estate offers 5 bedrooms, an amazing waterfront office, an expansive game room, an indoor gym, 4 full bathrooms, 2 half...

6707 Daniel Court

4 4.0   Sf: 3441   Yr: 1998  Acres: 0.446

Positioned on a SW Exposure point lot in Palmetto Point, this exceptional waterfront estate delivers one of Fort Myers' most sought-after boating lifestyles, with 220 feet of direct water frontage...

18090 N Olga Drive

6 5.0   Sf: 6294   Yr: 1993  Acres: 1.540

A rare Riverfront estate offering privacy, scale, and true deep-water boating. This property is truly special! As you approach the home, an expansive grand driveway entrance leads to a private estate...

Caloosahatchee River Information

The Caloosahatchee River is one of Florida's major waterways and serves as a vital resource for the surrounding communities. Here is some information regarding the river, as well as details about fishing and boating opportunities:

Overview
- Location: The Caloosahatchee River runs from Lake Okeechobee in the east to the Gulf of Mexico in the west, flowing through parts of Hendry and Lee counties.
- Length: Approximately 75 miles long.
- Ecology: The river passes through various ecosystems, including estuarine environments, wetlands, and urban areas. It is home to a diverse array of wildlife, including fish, birds, and other aquatic species.

Fishing
- Species: The river offers a variety of fishing opportunities. Common species include bass, snook, redfish, catfish, tarpon, and mullet.
- Fishing Spots: Some popular fishing areas include the bridges, docks, and natural shorelines along the river. There are also several parks and fishing piers, like the Fort Myers Yacht Basin and various spots along the river banks.
- Regulations: Anglers should be aware of Florida's fishing regulations, including size and bag limits, which can vary by species. Licenses are typically required and can be obtained online or at local retailers.

Boating
- Accessibility: The Caloosahatchee River is navigable and serves as a popular route for both recreational and commercial boating. There are several public boat ramps within Lee County for easy access.
- Activities: Common boating activities include kayaking, canoeing, motorboating, and sailing. The river's calm waters make it suitable for various skill levels.
- Wildlife Viewing: Boaters can enjoy the scenic beauty of the river and may encounter wildlife such as manatees, dolphins, and numerous bird species.

Safety and Regulations
- Boating Regulations: Familiarize yourself with local boating regulations, including speed limits, no-wake zones, and any designated manatee protection areas.
- Safety: Always wear life jackets, maintain proper safety equipment on board, and be mindful of changing weather conditions.

Points of Interest
- Caloosahatchee Regional Park: A popular recreational area that provides access to trails, fishing spots, and picnic areas.
- West Coast of Florida: The river leads to the Caloosahatchee estuary, where you can explore more remote areas and appreciate Florida's natural beauty.

The Caloosahatchee River is an essential part of Lee County's landscape and offers a variety of recreational opportunities. Whether you're fishing, boating, or simply enjoying the scenery, the river is a wonderful resource for both locals and visitors. Always practice sustainable fishing and boating to help preserve the natural environment for future generations.

If you're interested in specific real estate options, amenities, or activities around the lake, feel free to ask a Lake Real Estate Specialist!