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Looking for lakefront homes for sale on Lake De Soto? Find waterfront real estate here. Nearby cities include Lake City, Columbia County, Florida. Discover the best lake front listings - properties, land, and acreage to build your dream lake house, cottage or cabin on. Search for a lake real estate agent who specializes in Lake De Soto property to help you buy or sell a home.

Lakehouse.com has 1 lake property for sale on Lake De Soto, as well as lakefront homes, lots, land and acreage in Lake City. Median home price: $159,000. 

656 Lake Drive

3 1.0   Sf: 1243   Yr: 1943  Acres: 0.298

LAKE CITY - 1943 Cracker-Style Home | 3BR / 1BA | 1,243 Sq Ft (Heated & Cooled). Offering spacious living and vintage interior details throughout. Floor plan includes three bedrooms, a living room...

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Showing 10 lake properties within 20 miles:

5534 150th Place

3 2.0   Sf: 1216   Yr: 1994  Acres: 10.050

Horse Lover's Dream - 10 Acres, 10 Stall Barn, Fenced Pastures, & a Move In Ready Home! Situated on a spacious and serene piece of land with gorgeous old oak trees, this farm features a...

The Meadows

294 SW COLUMBIA AVE

3 2.0   Sf: 1526   Yr: 1947  Acres: 0.253

Charming 3-bedroom, 2-bathroom home with spacious fenced backyard situated on corner lot in Lake City. Home offers 1,526 sq. ft. of heated & cooled living space with a total of 2,654 sq. ft. under...

1258 SW SISTERS WELCOME ROAD

5 5.0   Sf: 4383   Yr: 1999  Acres: 9.860

Welcome to your own private estate -- a true masterpiece of luxury living! Tucked behind a gated entrance with an automatic gate, this exquisite property offers elegance, privacy, and functionality...

260 S Marion Avenue

0 0.0   Sf: 16050   Yr: 1975  Acres: 0.960

Fantastic Investment Opportunity! Executive Park Complex features 4 buildings with a total of 8 fully leased units, offering steady income from day one. Conveniently located near major thoroughfares...

Not on the List

1376 SW RIVERSIDE AVENUE

3 2.0   Sf: 1649   Yr: 1999  Acres: 0.816

Experience true Old Florida living with this one-of-a-kind cedar-sided home nestled along the crystal-clear waters of the Ichetucknee River in North Central Florida. Surrounded by natural beauty and...

Three Rivers Estates

292 SW OLD CYPRESS WAY

4 3.0   Sf: 4250   Yr: 2020  Acres: 0.550

*** VIEW OUR VIRTUAL VIDEO TOUR*** An extraordinary opportunity awaits at **The Reserve at Jewel Lake**, where luxury, privacy, and natural beauty converge. STUNNING LAKE ACCESS. HUGE. ADDITIONAL LOT...

RESERVE/JEWEL LAKE PH 1

498 Manatee Ter

3 2.0   Sf: 2628   Yr: 1973  Acres: 0.890

Experience the beauty of true North Florida river living in Fort White, just off the crystal-clear waters of the Santa Fe River. Situated on almost a full acre, this gated and fully fenced 3 bedroom...

Three Rivers Estates

258 SW Columbia Avenue

0 0.0   Sf: 8800   Yr: 1976  Acres: 1.010

Investment Opportunity! Own this 8,800 sq. ft. building, currently leased to a daycare center. Steady income and strong location make this a smart investment. Conveniently located near major...

264 NW SYLVI DRIVE

4 3.0   Sf: 3003   Yr: 2025  Acres: 0.000

Proud to present this newly constructed 4-bedroom, 2.5 bathroom lake-front home where architectural elegance meets intentional design, nestled on a one-acre homesite in the sought-after enclave of...

STARLAKE ESTATES

8850 SE 126TH CT

4 2.0   Sf: 2216   Yr: 1992  Acres: 10.000

Stunning Suwannee Riverfront Retreat - 10 Acres with Two Custom Homes Located in White Springs, FL, this rare 10-acre estate offers an incredible opportunity to own two fully custom-built homes on...