Ad #7988727
MLS #GC541231
Under contract-accepting backup offers. Some homes check the
7521 NE 222ND St, Melrose, FL 32666
$595,000
2Beds
2Baths
1,042Sqft
0.700Acres
About this property
Under contract-accepting backup offers. Some homes check the boxes. Others make you feel something the moment you arrive. Originally built in 1956 as two neighboring fish camps, this one-of-a-kind waterfront home has been thoughtfully transformed into a warm, inviting retreat while preserving the character that makes it so special. Sitting on 0.7 acres with more than 100 feet of shoreline on Big Lake Santa Fe, this is the kind of property where mornings begin with breathtaking sunrises over the water and evenings end on the porch after a day on the lake. With nearly 500 acres of surface water and depths reaching up to 26 feet, Big Lake Santa Fe is one of North Central Florida's most treasured lakes, offering year-round boating, skiing, fishing, paddleboarding, and endless days on the water. The property even includes its own natural lagoon with a small boat ramp, and the dock was extensively improved in 2023 with new pilings where needed, an extended platform, and a 5,000-pound Dolphin boat lift ready for your ski boat or pontoon. Inside, every room reflects the care and creativity of the current owners. The remodeled kitchen features custom cabinetry, updated countertops, appliances, and fixtures, while beautiful luxury vinyl plank flooring flows throughout the living spaces and new tile enhances both bathrooms. Thoughtful details-from the wood accents and designer lighting to the carefully chosen finishes-create a home that feels both timeless and effortlessly welcoming. One of the highlights is the incredible 31-foot screened porch, added in 2020. It's the perfect place to sip your morning coffee as the sun rises over the lake, watch afternoon storms roll across the water, or gather with friends long after the sun goes down. The home offers 2 bedrooms, 2 baths, plus a versatile bonus room that could easily serve as a third bedroom, office, bunk room, or creative studio. A unique guest bath connects directly to the utility room and exterior door, making cleanup after swimming, fishing, or working outdoors incredibly convenient. Outside, the property continues to impress. Mature cypress trees frame the lake without stealing the view, while a fully fenced yard with an electric gate offers privacy and peace of mind. A powered workshop and separate storage shed provide plenty of space for tools, hobbies, lake toys, and equipment. Nearly every major component has been improved, including a metal roof, updated windows and doors, remodeled kitchen and bathrooms, luxury flooring, exterior paint, new water heater (2026), gutters with guards, finished laundry room, sump pump (2021), septic service, and much more-allowing the next owner to simply move in and start enjoying lake life. Whether you're searching for a full-time residence, a weekend escape, or a vacation rental with exceptional appeal, this property offers something that's becoming increasingly difficult to find: authentic character, modern updates, and a front-row seat to one of North Central Florida's most beautiful lakes. Some houses are just places to live. This one is where memories are made. Need more room for family or guests? The beautifully built 2021 custom home directly across the street is also available. Purchase both together at a discounted package price to create your own private Big Lake Santa Fe retreat. (GC541232)
Property Features
2 Beds
2 Baths
1,042 Sqft
Built in 1956
0.700 Acres
1 Story
Santa Fe Lake
View Type: Lake, Water
Lakeview
On Waterfront
Siding: Concrete
Metal Roof
Central
$4,840 / yr property tax
Alachua County
Additional Photos
Contact Information
Lindsey Johnson
Keller Williams Gainesville Realty Partners
352-663-4347
Location
LakeHouse.com
Printed Jul 28, 2026
Photo Gallery
$595,000
2
Beds
2
Baths
1,042
Sqft
7521 NE 222ND St, Melrose, FL 32666
By contacting this agent you agree to these Terms and Conditions.
MLS# GC541231
Under contract-accepting backup offers. Some homes check the
$595,000
7521 NE 222ND St, Melrose, FL 32666
2
Beds
2
Baths
1,042
Sqft
0.700
Acres
$595,000
7521 NE 222ND St, Melrose, FL 32666
2 Beds
2 Baths
1,042 Sqft
0.700 Acres
Under contract-accepting backup offers. Some homes check the boxes. Others make you feel something the moment you arrive. Originally built in 1956 as two neighboring fish camps, this one-of-a-kind waterfront home has been thoughtfully transformed into a warm, inviting retreat while preserving the character that makes it so special. Sitting on 0.7 acres with more than 100 feet of shoreline on Big Lake Santa Fe, this is the kind of property where mornings begin with breathtaking sunrises over the water and evenings end on the porch after a day on the lake. With nearly 500 acres of surface water and depths reaching up to 26 feet, Big Lake Santa Fe is one of North Central Florida's most treasured lakes, offering year-round boating, skiing, fishing, paddleboarding, and endless days on the water. The property even includes its own natural lagoon with a small boat ramp, and the dock was extensively improved in 2023 with new pilings where needed, an extended platform, and a 5,000-pound Dolphin boat lift ready for your ski boat or pontoon. Inside, every room reflects the care and creativity of the current owners. The remodeled kitchen features custom cabinetry, updated countertops, appliances, and fixtures, while beautiful luxury vinyl plank flooring flows throughout the living spaces and new tile enhances both bathrooms. Thoughtful details-from the wood accents and designer lighting to the carefully chosen finishes-create a home that feels both timeless and effortlessly welcoming. One of the highlights is the incredible 31-foot screened porch, added in 2020. It's the perfect place to sip your morning coffee as the sun rises over the lake, watch afternoon storms roll across the water, or gather with friends long after the sun goes down. The home offers 2 bedrooms, 2 baths, plus a versatile bonus room that could easily serve as a third bedroom, office, bunk room, or creative studio. A unique guest bath connects directly to the utility room and exterior door, making cleanup after swimming, fishing, or working outdoors incredibly convenient. Outside, the property continues to impress. Mature cypress trees frame the lake without stealing the view, while a fully fenced yard with an electric gate offers privacy and peace of mind. A powered workshop and separate storage shed provide plenty of space for tools, hobbies, lake toys, and equipment. Nearly every major component has been improved, including a metal roof, updated windows and doors, remodeled kitchen and bathrooms, luxury flooring, exterior paint, new water heater (2026), gutters with guards, finished laundry room, sump pump (2021), septic service, and much more-allowing the next owner to simply move in and start enjoying lake life. Whether you're searching for a full-time residence, a weekend escape, or a vacation rental with exceptional appeal, this property offers something that's becoming increasingly difficult to find: authentic character, modern updates, and a front-row seat to one of North Central Florida's most beautiful lakes. Some houses are just places to live. This one is where memories are made. Need more room for family or guests? The beautifully built 2021 custom home directly across the street is also available. Purchase both together at a discounted package price to create your own private Big Lake Santa Fe retreat. (GC541232)
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Contact Information
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Listing Agent
Lindsey Johnson
Keller Williams Gainesville Realty Partners
Listing Agent: Lindsey Johnson 352-663-4347. Broker: Keller Williams Gainesville Realty Partners 352-240-0600 Listing Site. Copyright © 2026 Stellar MLS. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.
Property Details
HOME DETAILS
2 Beds
2 Baths
1,042 Sqft
Built in 1956
0.700 Acres
1 Story
WATER & VIEW
Santa Fe Lake
View Type: Lake, Water
Lakeview
On Waterfront
EXTERIOR
Siding: Concrete
Metal Roof
INTERIOR
Central
FINANCIAL & COMMUNITY
$4,840 / yr property tax
Alachua County
See More Details
Location
Mortgage Calculator
About Santa Fe Lake
Looking for lakefront homes for sale on Santa Fe Lake? Find waterfront real estate here. Nearby cities include Melrose and Melrose. Santa Fe Lake is located in Bradford and Alachua counties. Discover the best lake front listings - properties, land, and acreage to build your dream lake house, cottage or cabin on. Search for a lake real estate agent who specializes in Santa Fe Lake property to help you buy or sell a home.
Boating
Swimming
Jet Skiing
Lake Depth : Max 40'
Water Level : Water Levels Tend To Stay Fairly Constant.
Ad Statistics
Ad Number
7988727
Viewed
69 times
Listing Status
Active Under Contract
Added
Jun 27, 2026
Last Refresh
Jul 28, 2026 08:05:58 AM
Listing Information
Data Source
Stellar MLS
Source Property ID
GC541231
All information provided is deemed reliable but is not guaranteed and should be independently verified.
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