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Lakehouse.com has 5 lake properties for sale on Santa Fe Lake, as well as lakefront homes, lots, land and acreage in Earleton, Melrose, Waldo. Median home price: $481,725, lot price: $325,000. 

601 SE 4TH AVENUE

3 2.0   Sf: 1371   Yr: 2023  Acres: 0.570

Adorable 3 bedroom 2 bath home in Seminole Ridge with access to Lake Santa Fe with membership! Just grab your kayak and walk across the way to paradise! Open floor plan for a spacious feel for...

Ronald Blake, Agent

00 SE 5TH AVENUE

Acres: 0.610

Don't miss this rare opportunity! Discover the perfect chance to create your dream lakefront retreat on the highly sought-after Big Lake Santa Fe! Nestled in the desirable Seminole Ridge community...

Ronald Blake, Agent

303 SE 3RD Avenue

3 2.0   Sf: 2425   Yr: 1997 

Old Florida Charm with Modern Comfort welcomes you home to peace and quiet in this charming Old Florida-style neighborhood. This custom-built Florida Cracker-style home sits on just over half an acre...

NE 209 WAY lot: 16

Acres: 11.010

Your ONE-OF-A-KIND opportunity to build a waterfront estate for your family is NOW offered for sale! A primary home or vacation home, this private 11.04-acre estate is in a gated community, located...

468 SE 18TH Street

2 2.0   Sf: 1156   Yr: 1958 

Welcome to this charming 2-bedroom, 2-bath home in the heart of Melrose. Built in 1958 with 1,156 sq ft of living space, this well-maintained property features classic terrazzo floors, an updated...

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Showing 10 lake properties within 20 miles:

21215 SE 111TH AVENUE

6 3.0   Sf: 2041   Yr: 1978  Acres: 5.000

PRICE IMPROVEMENT !! LOCATED IN LAKE SHORE GARDENS !!! TWO HOMES FOR THE PRICE OF ONE !!! This unique property features two homes. The First home, originally built in 1930, has three bedrooms and one...

Ronald Blake, Agent

5949 SE COUNTY ROAD 21B

4 3.0   Sf: 1951   Yr: 2025  Acres: 0.510

Under Construction. Be the First to Call This Home! This beautiful new construction home sits in the heart of Melrose, FL. This home offers the perfect opportunity to secure your place in a brand-new...

Ronald Blake, Agent
INDIAN LAKE RANCH PHASE 1

5557 COUNTY ROAD 352

3 1.0   Sf: 1800   Yr: 1960  Acres: 0.810

Sellers will contribute closing costs or rate buydown with an approved offer by the sellers. DON'T MISS OUT! This fully remodeled and fully upgraded 3/1 home on White Sands Lake with almost an acre...

Ronald Blake, Agent
MCKAYS PRCL 1

89 TUCKER LAKE ROAD

Acres: 1.880

This beautiful waterfront lot with pines and palms winding down to picturesque view of the lake makes a great homesite location and boasts nearly 2 acres! No CDD fees and no HOA. No buildings other...

Ronald Blake, Agent

589 SE 71ST STREET

3 2.0   Sf: 1802   Yr: 1993  Acres: 0.690

Welcome to Crystal Lake Homesites. This Brick home is a two block walk to the lake. For a small yearly fee you can be a member and enjoy member only access to Crystal Lake, the concrete boat ramp...

Dean Weaver, II, Agent
CRYSTAL LAKE HOMESITES

7634 AZTEC COURT

4 4.0   Sf: 2653   Yr: 2009  Acres: 0.870

This Is the Home You've Been Waiting For! Welcome to your private oasis a stunning gated home that offers everything you need for luxury living and peaceful relaxation. Enjoy your own heated swimming...

Nelda Hoffmeyer, Agent
FLORIDA FRONTIER

5955 SE COUNTY ROAD 21B

4 3.0   Sf: 1981   Yr: 2025  Acres: 0.510

Under Construction. Be the First to Call This Home! This beautiful new construction home sits in the heart of Melrose, FL. This home offers the perfect opportunity to secure your place in a brand-new...

Ronald Blake, Agent
INDIAN LAKE RANCH PHASE 1

10503 SE US HWY 301

Acres: 5.200

5.20 acres with plenty of room for a couple of horses or cows. Property has been recently cleared and fenced, New culvert installed to provide access from and to US 301. Close to Holden Park Boat...

Ronald Blake, Agent

00 STATE ROAD 100

Acres: 9.850

Unlock the full potential of this exceptional 9.85-acre property, ideally positioned with direct frontage on the serene Brooklyn Lake and the popular Rails-to-Trails pathway. Located in Bradford...

Ronald Blake, Agent

651 N STATE ROAD 21

3 2.0   Sf: 1568   Yr: 1986  Acres: 19.510

This is more than land - it's a rare opportunity to own a fully operational, income producing farm with the flexibility to live, build, or invest your way. Turnkey farm - livestock ready...

Metes & Bounds

Santa Fe Lake photo

Ron Blake: Santa Fe Lake Real Estate Agent Info

C.B. Isaac Realty was established in 1975 in Melrose, Florida by Mr. Clinton Isaac and has been a local landmark ever since. Located on State Road 21 at the junction of four counties (Alachua, Bradford, Clay & Putnam) the office has grown with the community. The company has been known throughout North Florida for marketing land, waterfront, and commercial properties. In 2002 the company was purchased by Alvin E. Reynolds and Ronald E. Blake who have expanded the company with offices in Jacksonville, Gainesville, Hawthorne, and Melrose/Keystone Heights we are able to provide our customers with maximum exposure whether you are buying or selling a property, or looking for a short sale or foreclosure. The company was the Lake Regions' top sales and listing office for the last two years. CB Isaac Realty has been providing exceptional real estate services to North Florida and South Georgia and we have put together a highly qualified team of professionals with a focus on Unique Residential Properties, Commercial Properties, Farms, Ranches, and Land including Development, Timberland Investments and Recreational for the outdoor enthusiast. We are a full-service company Specializing in Large Acreage Tracts, Farms & Ranches, Waterfront, Commercial, and Unique Residential Properties. We serve all of North Florida, Central Florida, South Georgia & the Caribbean with a staff of experienced and dedicated associates.

Santa Fe Lake Information

Santa Fe is actually two lakes, Big Lake Santa Fe and Little Lake Santa Fe which are connected by a mile wide pass. The state shows little Lake Santa Fe at 1,134 acres and the big lake at 4,813 acres or a total of 6,000 acres.

The lake is the headwaters for the Santa Fe river which starts at the north end of the lake and feeds into the Santa Fe swamp a 10,000 acre water shed controled by the State Water Management folks.

The lake is a full service waterbody with jet-ski's, swimming, boats of all kinds, seaplanes and with some of the best fishing in the state. The lake is also rated as one of the top four lakes in the state of Florida and is labeled an "Outstanding Waterbody". Lake Santa Fe is designated by the State of Florida as an Outstanding Florida Water which, according to the Florida Department of Environmental Protection, means it is “worthy of special protection because of its natural attributes.”

Depths can reach 40 feet in spots and there is several canals leading to other lakes (Lake Alto & such) which back in the day paddle boats transported citrus from Melrose on the south shore on paddle boats across the lake, through the canals to Waldo train station northwest of the lake.

The nearest towns are Melrose on the south end on the lake and Keystone Heights to the northeast about one mile. Gainesville is a 20 minute drive and Jacksonville about 50 minutes.

The lake borders on three counties (Alachua, Bradford & Putnam) with each county having a little different requirements to build.

Santa Fe Lake is a popular body of water located in Melrose, Florida, known for its recreational opportunities, including fishing and boating. Here are some details about the lake:

Fishing
- Fish Species: Santa Fe Lake is home to a variety of fish species, including largemouth bass, bluegill, catfish, and crappie. The lake's health and biodiversity can vary based on factors like water levels and vegetation.
- Fishing Methods: Anglers can enjoy shore fishing, boat fishing, and bank fishing. It's advisable to check local regulations regarding fishing licenses and limits.
- Seasons: Fishing can be good year-round, but certain seasons may offer better success rates, such as the spring spawning period for bass.

Boating
- Boat Access: There are public boat ramps and access points on the lake, making it accommodating for both small and larger boats. Kayaking and canoeing are also popular on the lake due to its relatively calm waters.
- Types of Watercraft: Motorized boats are permitted, but it's important to be mindful of speed limits and idle zones to ensure safety and protect the local environment.
- Safety: Always wear life jackets and be aware of other boaters, as well as any designated swimming areas or no-wake zones.

Amenities
- Parks and Facilities: Some areas around the lake may have parks with picnic facilities, restrooms, and access to walking trails for a full day of outdoor activities.
- Wildlife: The area around Santa Fe Lake provides a habitat for various wildlife, including birds and other small animals, which can enhance the natural experience for visitors.

Local Tips
- Weather: Check the weather conditions before heading out for fishing or boating as storms can develop quickly in Florida.
- Local Bait Shops: There may be local bait and tackle shops nearby where you can purchase supplies and get the latest fishing reports.
- Community Events: Occasionally, local organizations host fishing tournaments or community events that might be of interest if you're visiting the area.

Santa Fe Lake in Melrose, Florida, offers a great escape for fishing and boating enthusiasts. Whether you're looking to catch some fish or just enjoy a day on the water, the lake presents a picturesque setting with plentiful options for recreation. Always remember to follow local regulations and practice responsible fishing and boating.

If you're interested in specific real estate options, amenities, or activities around the lake, feel free to ask a Lake Real Estate Specialist!

For More Lake Information:  http://www.lakesantafe.org

Are Jet Skis permitted on Santa Fe Lake? Yes
Can you Swim in Santa Fe Lake? Yes
What is the Average water level variance at Santa Fe Lake? Water levels tend to stay fairly constant.
Are Boat Docks permitted at Santa Fe Lake? Yes
Are Power Boats permitted at Santa Fe Lake? Yes
What is the Lake Depth at Santa Fe Lake? max 40'
What are the Nearby Cities to Santa Fe Lake? Melrose, Keystone Heights, Gainesville - 20 min
What is the Closest Airport to Santa Fe Lake? Nearest airport would be Gainesville (15 miles) with Keystone having a Ga field (42J).